General Statement Research on high-polymer fucoidan

Research achievements on anticancer effects and the reduction of side-effects related to anticancer drugs

  • Anticancer effects (animal clinical tests)
  • Reduction of side-effects (human clinical tests)

Research achievements on prevention of lifestyle-related diseases and reduction of disease risks

  • Gout
  • Thrombosis
  • Joint pain

Research achievements to live a comfortable life

  • Enteral environment
  • Hangover

What's Fucoidan

  • What is high-polymer fucoidan?
  • History of fucoidan research


  • The development trajectory of our fucoidan production technology
  • The Cadre of Professional Researchers for fucoidan


  • Academic papers
  • Application of Patents
  • Presentations at academic conferences
  • Joint research
  • Fucoidan Tsushin News Letter
  • Promotional Video


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"General Statement" Research on High-Polymer Fucoidan ~The trajectory of Marine Products Kimuraya R&D Division~

Established R&D Division to enhance quality control of our products

Marine Products Kimuraya building

"We want to deliver tasty, reliable and safe food to customers" is our corporate philosophy since the foundation of Marine Products Kimuraya who have been producing and selling mainly mozuku products.

This is our original and intending mind of R&D.

In 1987, our R&D Division was established to conduct further thorough quality control and hygiene management.

Then the research from the scientific perspective started.

In 1994, the joint research with Shimane University, Faculty of Agriculture (currently, Faculty of Life & Environmental Science) started.

We dispatched our researcher to the University laboratory for further studies posing research themes such as quality retention and fermentation control.

The incident which shook trust in food, became a trigger.

Microscope photograph of E.coli O-157

In 1996, the outbreak of the group infection occurred by enterohemorrhagic E. coli O-157 (the so called "O-157 incident"), primarily among children and the elderly.

This incident caused widespread illnesses and some deaths throughout

Under these serious circumstances, to confirm the safety of our products, we initiated joint research with Shimane University to investigate the effects of mixing E. coli O-157 in our seasoned mozuku.

Surprisingly we learned that E. coli O-157 was killed in the seasoned

It was also shown that verotoxin (verotoxin is a pathogenic factor that causes bloody diarrhea, hemolytic-uremic syndrome, and acute encephalopathy) was not produced.

Generally verotoxin is produced in the body of patients in which E. coli O-157 itself is being killed. The verotoxin caused serious symptoms.

By following further researches, it was confirmed that viscous parts of mozuku had components that presented antivirus activity.

We found that mozuku effectively suppressed side-effects caused by anticancer drugs

Influence on cancer cells when adding fucoidan.A: Normal cancer cells(actively proliferate andstick to the culture vessel) B: Cancer cells when adding fucoidan(suppressed proliferation and curl-up)

Our R&D Division and the team of Shimane University Faculty of Life & Environmental Science confirmed that the useful constituent that presented antibacterial properties was the same constituent of fucoidan.

This existence of this constituent in fucoidan was first confirmed in 1913, by Prof. Kylin, of Uppsala University in Sweden.

Since then research has been carried out in various countries.

In the 1980s the anticancer effects of fucoidan started receiving attention.

In our joint research with Shimane University, we confirmed that fucoidan extracted from mozuku in the laboratory had the effect of suppressing the proliferation of cancer cells and the suppressed the side-effects caused by anticancer drugs.

Our joint research with Tottori University Faculty of Medicine is identifying biological activity

Tottori University Faculty

In 2004, we participated in a research project sponsored by the Ministry of Education, Culture, Sports, Science and Technology ("City Area Industry, Academia, Government Cooperation Program" in Yonago City and Sakaiminato City, Tottori Prefecture).

On this occasion we started exchanging information with Tottori University Faculty of Medicine.

Through these collaborations, our method of clarifying the mechanism of biological activity of our mozuku fucoidan was further confirmed, from the basal level research using cultivated cells to more pragmatic verification from animal and human clinical tests.

For the "City Area Industry, Academia, Government Cooperation Program", in 2006-2008, we provided our fucoidan as research material.

We conducted joint research, with Tottori University Faculty of Medicine, Faculty of Agriculture, Faculty of Engineering, Tottori Institute of Industrial Technology, on the "Construction of evaluation system of food developed, through chromosomal engineering, to prevent lifestyle-related disease, and the development of food products".

After 3 years of research, it was confirmed that: [1] fucoidan effects lead to prevention of gout; [2] fucoidan effects lead to prevention of blood clots; [3] fucoidan helps promote regeneration of cartilage; and [4] fucoidan has anticancer activity.

Based on this research, we have great expectations that the useful effect of fucoidan will continue to be discovered and confirmed in the years ahead.

Our joint research with Tottori University Faculty of Medicine, Faculty of Agriculture, Faculty of Engineering and others continues today.

We have achieved a great number of outstanding results, and we are gathering the attention of researchers worldwide.

We are pleased to introduce the results of the animal and human clinical tests we have conducted in collaboration with a wide variety research institutes.

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